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Published on: February 19, 2019
Hepatitis B viral markers in Nigerian patients with primary liver carcinoma
1Department of Medicine, University of Maiduguri Teaching Hospital, Nigeria.
Abstract:
Sera from 65 patients with primary liver carcinoma (PLC) and 69 sex- and age-matched controls were examined for Hepatitis B virus markers. Forty two of the patients (65%) and 25 controls (36%) were HBsAg positive. Anti-HBc was demonstrated in over 80% and in 84% of the study groups respectively. Over 70% of hepatitis B infection was anicteric and traditional surgical intervention correlated with prevalence of PLC. The data provide support for the etiological role of HBV in Nigerian patients with PLC; this is the first report that the incidence of PLC is highest in the northern Savannah region of Nigeria.
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