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Published on: May 17, 2024
Giant apocrine hidradenoma of the breast
Darly Knoedler1, Barbara Susnik, Mary Beth Gonyo
1Department of Pathology, Medical College of Wisconsin, Miwaukee, Wisconsin 53226, USA. dknoedle@mcw.edu
Abstract:
We report a case of a 26-year-old woman with an 8.0-cm tumor of the left breast. The tumor was clinically and radiologically suspicious for malignancy. The pathologic evaluation of the core biopsy and the subsequent excision specimen revealed a benign sclerosing, cystic, and papillary adnexal tumor with apocrine and clear cell morphology. The immunohistochemical staining for p63 was positive. Estrogen, progesterone, and Her-2 receptor immunohistochemical stains were negative. The cytogenetic analysis revealed 46, XX t(11:19) (q21;q13.1) balanced translocation. The final diagnosis was apocrine hidradenoma.
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