Related Experiment Video
Updated: Jul 17, 2026

Methods to Test Endocrine Disruption in Drosophila melanogaster
Published on: July 3, 2019
Polychlorinated dibenzothiophenes in Japanese environmental samples and their photodegradability and dioxin-like
Satoshi Nakai1, Saeko Kishita, Yugo Nomura
1Department of Chemical Engineering, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8527, Japan. nakai@hiroshima-u.ac.jp
Abstract:
Polychlorinated dibenzothiophenes (PCDTs) in sediment, soil, and fly ash samples collected in Japan were analyzed and their dioxin-like endocrine-disruption potential and photodegradability investigated. PCDTs were detected in all three types of sample, although the concentrations were lower than those of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). An Ah-immunoassay confirmed that 2,3,7,8-TeCDT, 1,2,3,7,8-PeCDT, 1,2,3,7,8,9-HxCDT, and 1,2,3,4,7,8,9-HpCDT had Ah receptor-binding activities, which means that these PCDTs have the potential to cause dioxin-like endocrine-disruption. Photodegradation of PCDTs by UV irradiation was accompanied by dechlorination. The photodegradation rates of 2,3,7,8-TeCDT and OCDT were lower than the rates for the corresponding PCDF isomers (2,3,7,8-TeCDF and OCDF), which indicates that PCDTs are more stable than PCDFs to photodegradation.
More Related Videos
Related Concept Videos
Microbial Bioremediation of Pesticides
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Toxicity Testing in Animals

