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Subepidermal calcified nodule in a 7-month-old boy
Yaohui Xu1, Vesna Petronic-Rosic, Sarah L Stein
1Section of Dermatology, Department of Medicine, University of Chicago Hospitals, Chicago, IL 60637, SUA.
Insights
A rare skin condition, subepidermal calcified nodule (SCN), presented as a growing papule on an infant's ear. Histologic analysis confirmed the diagnosis, and surgical removal yielded positive results.
Area of Science:
- Dermatology
- Pathology
- Pediatrics
Background:
- Subepidermal calcified nodule (SCN) is an uncommon, idiopathic condition.
- It typically presents as a solitary nodule, often on the head or neck.
Observation:
- A 7-month-old boy presented with a gradually enlarging papule on his right ear, noted shortly after birth.
- Physical examination revealed a 5-6 mm pink, firm papule with a scaly surface and surrounding erythema on the superior helix.
Findings:
- Histologic examination showed epidermal defect with fibrin, chondroid tissue, granulation tissue, and extensive amorphous calcified material in the dermis.
- The findings were consistent with subepidermal calcified nodule (SCN).
Implications:
- Early diagnosis and surgical excision are effective for subepidermal calcified nodules.
- This case highlights the presentation of SCN in infancy, emphasizing the importance of histopathological correlation.
Abstract:
A 7-month-old healthy white boy presented for evaluation of a papule on his right ear. His mother reported a small cut-like lesion at this site shortly after birth that had gradually grown over time. The patient was born full term via repeat cesarean section. On physical examination, located on the right superior helix, there was a 5-6 mm, pink, firm papule with a rough scaly surface and peripheral erythema (Figure 1). The lesion was shave excised and sent for histologic analysis. Microscopic examination revealed a defect of the epidermis with underlying fibrin deposits (Figure 2). Subjacent to the ulcer, there was chondroid tissue, granulation tissue with prominent vascularity, and an extensive amount of amorphous calcified material throughout the dermis extending to the base of the specimen (Figure 3). The clinical and pathologic findings were consistent with a subepidermal calcified nodule (SCN), an uncommon idiopathic calcinosis. The lesion was surgically removed with good results.
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