Ambulatory EEG cassette recorders for prolonged electroencephalographic monitoring in animals

We describe the use of ambulatory cassette EEG recorders for monitoring in vivo neurophysiologic signals from multiple animals over prolonged periods of time. This technique centers around a simple interface device that attenuates the intracerebral signals to the input range of the recording device and around a common indifferent input for all animals. The resulting analog recordings have the advantage of good signal resolution and rapid review of 24 h of recorded data.