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Updated: Jul 17, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Diagnosis and therapy of tumor related pain]
1Zentrum für Palliativmedizin, Kliniken Essen-Mitte, 45136, Henricistrasse 92, Essen, Deutschland. m.kloke@kliniken-essen-mitte.de
Abstract:
The World Health Organization guidelines for cancer pain therapy from 1986 are still valid. A prerequisite for adequate pain palliation is an exact anamnesis and pain diagnosis. A multimodal, staged therapeutic concept then needs to be formulated according to the requirements of the patient. The pharmacological treatment starts with non-opioids. If pain control remains insufficient, weak opioids are added. In case of persistent pain these are replaced by strong opioids. The availability of new opioids and/or preparations admits a more sophisticated approach to metabolic disorders and specific pain syndromes. Depending on the presenting pain type, co-analgesics might be added.
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