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Updated: Jul 17, 2026

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
Published on: March 17, 2015
TRPM3
1Institut für klinische und experimentelle Pharmakologie und Toxikologie der Universität des Saarlandes, 66421 Homburg, Germany. johannes.oberwinkler@uniklinikum-saarland.de
Abstract:
TRPM3 is the last identified member of the TRPM subfamily and is most closely related to TRPM1. Due to alternative splicing, the TRPM3 gene encodes a large number of different variants. One splice event, affecting the pore-forming region of the channel, changes its selectivity for divalent cations. In this review, we give an overview of the identified TRPM3 variants and compare their functional properties.
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