Related Experiment Video
Updated: Jul 17, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
[Systemic enzyme therapy in the treatment of children with lower orbital wall fractures]
Insights
Systemic enzyme therapy with Wobenzim in children with orbital wall fractures reduced inflammation and complications. This approach decreased the need for surgical repair compared to conventional therapy.
Area of Science:
- Ophthalmology
- Traumatology
- Pharmacology
Background:
- Orbital wall fractures can lead to complications like muscle strangulation and hernias.
- Early intervention is crucial for optimal healing and minimizing scar tissue formation.
- Systemic enzyme therapy offers a potential non-surgical approach to managing these injuries.
Purpose of the Study:
- To evaluate the efficacy of Wobenzim, a systemic enzyme therapy, in treating lower orbital wall fractures in children.
- To assess the impact of Wobenzim on healing conditions and scar tissue formation.
- To compare the outcomes of Wobenzim monotherapy with conventional therapy.
Main Methods:
- A study involving 26 children with lower orbital wall fractures treated with Wobenzim monotherapy within 7 days of injury.
- A control group of 24 patients received standard systemic dehydration and vessel-strengthening therapy.
- Outcomes measured included inflammatory manifestation duration, complication rates, and need for surgical intervention.
Main Results:
- Wobenzim therapy significantly reduced the time for inflammatory manifestations to subside.
- The treatment prevented complications such as inferior rectus muscle strangulation and orbital soft tissue hernias.
- Fewer patients in the Wobenzim group required surgical plastic repair of the orbital wall compared to the control group.
Conclusions:
- Systemic enzyme therapy with Wobenzim is effective in managing pediatric orbital wall fractures.
- Wobenzim improves healing, reduces inflammation, and prevents serious complications.
- This therapy offers a viable alternative to surgery in a substantial number of cases.
Abstract:
Wobenzim, a drug for systemic enzyme therapy, was used in 26 children with lower orbital wall fractures as monotherapy in early periods (on days 1 to 7) after brain injury to improve healing conditions and to minimize the formation of scar tissues in the fractural area. A control group comprised 24 patients who received systemic dehydration and vessel-strengthening therapy. Systemic enzyme therapy with Wobenzim could reduce the attenuation time of inflammatory manifestations of injury, prevent complications, such as strangulation of the musculus rectus inferior in the fractural area and development of strangulated orbital soft tissue hernia, and substantially decrease the number of patients having indications for surgical plastic repair of the orbital wall, as compared with the control group.
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
