[Systemic enzyme therapy in the treatment of children with lower orbital wall fractures]

Vestnik Oftalmologii
|January 16, 2007
PubMed

Insights

Systemic enzyme therapy with Wobenzim in children with orbital wall fractures reduced inflammation and complications. This approach decreased the need for surgical repair compared to conventional therapy.

Area of Science:

  • Ophthalmology
  • Traumatology
  • Pharmacology

Background:

  • Orbital wall fractures can lead to complications like muscle strangulation and hernias.
  • Early intervention is crucial for optimal healing and minimizing scar tissue formation.
  • Systemic enzyme therapy offers a potential non-surgical approach to managing these injuries.

Purpose of the Study:

  • To evaluate the efficacy of Wobenzim, a systemic enzyme therapy, in treating lower orbital wall fractures in children.
  • To assess the impact of Wobenzim on healing conditions and scar tissue formation.
  • To compare the outcomes of Wobenzim monotherapy with conventional therapy.

Main Methods:

  • A study involving 26 children with lower orbital wall fractures treated with Wobenzim monotherapy within 7 days of injury.
  • A control group of 24 patients received standard systemic dehydration and vessel-strengthening therapy.
  • Outcomes measured included inflammatory manifestation duration, complication rates, and need for surgical intervention.

Main Results:

  • Wobenzim therapy significantly reduced the time for inflammatory manifestations to subside.
  • The treatment prevented complications such as inferior rectus muscle strangulation and orbital soft tissue hernias.
  • Fewer patients in the Wobenzim group required surgical plastic repair of the orbital wall compared to the control group.

Conclusions:

  • Systemic enzyme therapy with Wobenzim is effective in managing pediatric orbital wall fractures.
  • Wobenzim improves healing, reduces inflammation, and prevents serious complications.
  • This therapy offers a viable alternative to surgery in a substantial number of cases.