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Self-Administration of Drugs in Mouse Models of Feeding and Obesity
Published on: June 8, 2021
[Atypical antipsychotic-induced weight gain]
Beata R Godlewska1, Luiza Olajossy-Hilkesberger, Halina Marmurowska-Michałowska
1Klinika Chorób Psychicznych i Zaburzeń Nerwicowych AM w Gdańisku.
Psychiatria Polska
|January 16, 2007
Summary
Atypical antipsychotics offer improved efficacy for psychoses but can cause significant weight gain. This review examines the adverse effects of these drugs, focusing on weight gain and its clinical implications.
Area of Science:
- Pharmacology
- Psychiatry
Context:
- Atypical antipsychotics represent a newer class of drugs for treating psychoses, including schizophrenia.
- These medications differ from classical neuroleptics due to unique properties and mechanisms of action.
Purpose:
- To review the adverse effects of atypical antipsychotics, with a specific focus on weight gain.
- To discuss the clinical and subjective significance of weight gain associated with these medications.
Summary:
- Atypical antipsychotics provide a broader spectrum of action and high efficacy with fewer extrapyramidal symptoms compared to classical neuroleptics.
- However, side effects like sedation, metabolic changes, and significant weight gain have become prominent issues.
- Weight gain is a critical concern due to its association with severe somatic consequences and patient distress.
Impact:
- Highlights the need for careful monitoring of metabolic changes and weight gain in patients treated with atypical antipsychotics.
- Informs clinical practice regarding the management of adverse effects associated with these important psychiatric medications.
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