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Updated: Jul 17, 2026

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Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
[Change in the joint line after total knee arthroplasty]
Jun Li1, Tian-yue Zhu, Wei-bing Chai
1Department of Orthopaedics, the First Hospital of Peking University, Beijing 100034, China. jointline@263.net
Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|January 16, 2007
Summary
Sacrificing ligaments during knee replacement can lead to proximal joint line malpositioning. Surgeons can use specific bone landmarks to ensure correct prosthetic joint line placement during surgery.
Area of Science:
- Orthopedic Surgery
- Biomechanical Engineering
- Medical Imaging
Context:
- Total knee replacement (TKR) is a common procedure to alleviate pain and restore function in patients with knee osteoarthritis.
- Accurate restoration of the native joint line is crucial for optimal TKR outcomes.
- Ligamentous structures play a significant role in guiding joint line positioning during TKR.
Purpose:
- To evaluate the change in the joint line position following total knee replacement.
- To compare joint line changes between cruciate-retaining and rotational knee replacement systems.
- To identify reliable landmarks for achieving accurate joint line restoration in TKR.
Summary:
- This study analyzed lateral radiographs of 43 patients undergoing TKR with either cruciate-retaining or rotational prostheses.
- The change in joint line position (JL'-JL) was measured pre- and postoperatively.
- A significant proximal shift of the prosthetic joint line was observed when collateral and cruciate ligaments were sacrificed, with rotational systems showing a greater mean shift (3.1 mm) compared to cruciate-retaining systems (2.0 mm).
Impact:
- Findings suggest that sacrificing ligaments during TKR may result in unintended proximal malpositioning of the prosthetic joint line.
- The study highlights the importance of preserving or accurately restoring ligamentous balance for proper joint line alignment.
- Recommendations are made for utilizing fibular styloid and epicondylar landmarks to guide accurate joint line placement during TKR surgery.
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