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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

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Published on: January 18, 2018

Mechanical interventions to treat acute stroke.

David Fussell1, H Christian Schumacher, Philip M Meyers

  • 1Doris and Stanley Tananbaum Stroke Center, Neurological Institute of New York, New York, NY 10032, USA.

Current Neurology and Neuroscience Reports
|January 16, 2007
PubMed
Summary

Advances in neuroimaging are expanding treatment options for acute ischemic stroke beyond the traditional 3-hour window. Novel mechanical therapies show promise for improving outcomes in stroke patients.

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Area of Science:

  • Neurology
  • Biomedical Engineering
  • Interventional Cardiology

Background:

  • Acute ischemic stroke treatment is historically limited by few options and a narrow therapeutic window (within 3 hours).
  • Traditional therapies often fail to address the underlying clot causing cerebrovascular occlusion.
  • The need for improved and extended treatment options for stroke is critical.

Purpose of the Study:

  • To review novel mechanical therapies for acute ischemic stroke.
  • To highlight advancements in neuroimaging facilitating new treatment approaches.
  • To discuss the potential of interventional techniques to expand the therapeutic window.

Main Methods:

  • Review of recent studies on mechanical endovascular therapies for stroke.
  • Analysis of emerging technologies for clot disruption and extraction.
  • Examination of angioplasty and stenting in the context of acute ischemic stroke.

Main Results:

  • Several mechanical systems demonstrate potential efficacy hours after cerebrovascular occlusion.
  • Endovascular clot disruption and extraction show promising initial results.
  • Angioplasty with stenting is under investigation as a viable stroke treatment.

Conclusions:

  • Advancing neuroimaging and mechanical therapies are broadening treatment options for acute ischemic stroke.
  • New interventional techniques may extend the time window for successful stroke intervention.
  • Physicians have increasingly effective tools to manage acute ischemic stroke based on clinical scenarios.