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Related Experiment Video

Updated: Jul 17, 2026

Using Isolated Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High throughput Microplate Respiratory Measurements
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[Results after lidloading with rigid gold weights--a meta-analysis].

T Schrom1, K Wernecke, A Thelen

  • 1Klinik für Hals-, Nasen-, Ohrenkrankheiten, Universitätsmedizin Berlin, Charité Campus Mitte, Schumannstrasse 20/21, 10117 Berlin. thomas.schrom@gmx.de

Laryngo- Rhino- Otologie
|January 16, 2007
PubMed
Summary

Rigid gold implants for lagophthalmos (involuntary eyelid closure) show significant complication rates, including bulging and infection. Further research into alternative implants is recommended for improved treatment effectiveness.

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Area of Science:

  • Ophthalmology
  • Oculoplastics
  • Biomaterials

Context:

  • Rigid gold implants are utilized for surgical correction of lagophthalmos.
  • Existing studies on gold implants present varied complication rates and often involve small patient cohorts.
  • A meta-analysis is crucial for a comprehensive understanding of treatment outcomes.

Purpose:

  • To evaluate the postoperative results of rigid gold implants in lagophthalmos surgery.
  • To identify and quantify common complications associated with these implants.
  • To statistically compare findings with existing meta-analysis data.

Summary:

  • A meta-analysis of 38 publications involving 1000 rigid gold implants was conducted.
  • Successful lid closure was achieved in 84.5% of cases.

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  • Complication rates included 13.4% bulging, 6.4% migration, 6.8% extrusion, 11.5% corneal astigmatism, and 7.0% infection.

    • Impact:

    • Rigid gold implants demonstrate a notable incidence of postoperative complications.
    • The findings underscore the need to consider alternative implants to enhance treatment efficacy.
    • Lidloading with gold implants, while simple and reversible, necessitates careful consideration of associated risks.