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Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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In some cases, there...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Dosage Regimens: Partial Pharmacokinetic Parameters01:01

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It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...

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E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
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Published on: August 1, 2019

Evaluating sample medications in primary care: a practice-based research network study.

Laura B Hansen1, Joseph J Saseen, John M Westfall

  • 1University of Colorado, Health Sciences Center, Denver, USA. laura.hansen@uchsc.edu

Joint Commission Journal on Quality and Patient Safety
|January 16, 2007
PubMed
Summary

Primary care practices show poor adherence to medication sample safety guidelines. Inadequate labeling and patient instructions increase the risk of medication errors.

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Last Updated: Jul 17, 2026

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Published on: August 1, 2019

Area of Science:

  • Pharmacy practice
  • Patient safety
  • Primary care

Background:

  • Limited objective data exists on medication sample safety in primary care.
  • Medication errors are a significant concern in healthcare.

Purpose of the Study:

  • To assess primary care practice adherence to Institute for Safe Medication Practices (ISMP) recommendations for medication sample distribution.
  • To identify potential risks associated with current sample dispensing procedures.

Main Methods:

  • A two-phase observational study was conducted in 17 urban and rural primary care practices in 2004.
  • Methods included site visits for inventory and dispensing procedure assessment, and provider/patient surveys.

Main Results:

  • No practices fully complied with all seven ISMP recommendations.
  • Policies for dispensing and labeling were inconsistent across practices.
  • Patient education primarily relied on verbal communication, with inadequate information on appropriate use and side effects.

Conclusions:

  • Primary care practices exhibit deficiencies in safe medication sample dispensing.
  • Inadequate labeling and patient instructions pose a risk for medication errors.
  • Adherence to ISMP guidelines is crucial for improving patient safety.