[The treatment of periprosthetic infections]

C H Lohmann1, M Fürst, O Niggemeyer

  • 1Lehrstuhl für Orthopädie, Universitätsklinikum Hamburg-Eppendorf. LohmannCH@t-online.de

Insights

Periprosthetic joint infections (PJIs) are serious complications after total joint arthroplasty. Accurate diagnosis and tailored treatment, including debridement or revision surgery and antibiotic therapy, are crucial for successful outcomes.

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Microbiology

Context:

  • Periprosthetic joint infections (PJIs) are significant complications following total joint arthroplasty (TJA).
  • Risk factors include systemic diseases like rheumatoid arthritis and prior surgeries.
  • The incidence of PJIs in the studied cohort was 0.72%, with a recurrence rate of 23.4%.

Purpose:

  • To review diagnostic and treatment strategies for periprosthetic joint infections.
  • To highlight the importance of accurate preoperative bacterial diagnostics.
  • To discuss management algorithms for early and late-stage infections.

Summary:

  • Accurate preoperative diagnosis via joint fluid aspiration is essential for successful PJI management.
  • Early infections may be treated with debridement, while late or low-grade infections necessitate revision surgery.
  • Antibiotic therapy, particularly with rifampicin, is a mandatory component of treatment.

Impact:

  • This review provides insights into optimizing the management of PJIs.
  • It emphasizes the need for precise diagnostic methods and evidence-based treatment algorithms.
  • Improved PJI management can lead to better patient outcomes and reduced healthcare costs.

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