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Related Experiment Videos

[Surgery for Parkinson's disease].

A Kaelin-Lang1, A Stibal

  • 1Zentrum für Bewegungsstörungen, Neurologische Klinik, Universitätsspital, Bern. alain.kaelin@dkf.unibe.ch

Therapeutische Umschau. Revue Therapeutique
|January 16, 2007
PubMed
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Deep brain stimulation (DBS) surgery is a growing treatment for Parkinson's Disease (PD), effectively managing motor symptoms and reducing medication needs. However, long-term quality of life impacts and risks for patients with severe cognitive or axial symptoms require further study.

Area of Science:

  • Neurosurgery
  • Neurology
  • Movement Disorders

Background:

  • Parkinson's Disease (PD) management has seen a resurgence in surgical interventions.
  • Deep brain stimulation (DBS) has largely replaced older stereotactic lesioning techniques.

Purpose of the Study:

  • To review the current status and indications for surgical treatments in Parkinson's Disease.
  • To highlight the efficacy of DBS for motor complications and discuss patient selection criteria.

Main Methods:

  • Review of current surgical practices for Parkinson's Disease, focusing on Deep Brain Stimulation (DBS).
  • Discussion of target selection (subthalamic nucleus, globus pallidus internus, thalamus) and patient criteria.

Main Results:

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  • Bilateral DBS of the subthalamic nucleus is an established treatment for PD.
  • DBS effectively improves motor symptoms like dyskinesia, bradykinesia, tremor, and rigidity, allowing for medication reduction.
  • DBS of the globus pallidus internus and thalamus remain options for select patients.

    • Conclusions:

    • DBS is a valuable tool for managing motor complications in Parkinson's Disease unresponsive to medication.
    • Careful patient selection is crucial, excluding individuals with severe cognitive, psychiatric, or axial symptoms due to potential worsening.
    • Long-term effects of DBS on quality of life require further investigation.