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Preauricular sinus: clinical course and associations.
Xin Yong Huang1, Guan Sze Tay, Gervais Khin-Lin Wansaicheong
1Medical Classification Centre, Central Manpower Base, Ministry of Defense, Singapore.
Congenital preauricular sinus (PAS) is rarely associated with ear or renal abnormalities in young adults. However, about a quarter of PAS lesions can become symptomatic, often with recurrent discharge, even after age 16.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Medical Genetics
Background:
- Congenital preauricular sinus (PAS) is a common congenital malformation.
- PAS is often presumed to be associated with other congenital abnormalities, particularly of the ear and kidneys.
- The long-term clinical course and associated risks of PAS into adulthood are not well-established.
Purpose of the Study:
- To evaluate the clinical course of congenital preauricular sinus (PAS) in young adult males up to adulthood.
- To determine the association of PAS with congenital ear and renal abnormalities in this population.
Main Methods:
- A cohort survey design was employed.
- Medical screening data from 10,734 male subjects (median age 19 years) assessed for military conscription were analyzed.
- Subjects with PAS underwent pure-tone audiometry and renal ultrasonography to assess for associated abnormalities.
Main Results:
- A prevalence of 1.13% for PAS was identified in the study cohort.
- Associated hearing loss (sensorineural) and renal deformities were rare, found in only 1.7% and 2.6% of subjects, respectively.
- Approximately 24% of individuals with PAS developed symptoms, primarily recurrent sinus discharge, with nearly a third of these cases occurring after age 16.
Conclusions:
- Congenital preauricular sinus (PAS) in young adult males shows a rare association with ear and renal abnormalities.
- A significant proportion of PAS lesions can become symptomatic in late adolescence and early adulthood.
- Recurrent sinus discharge is the most common presenting symptom, highlighting the need for continued monitoring.
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