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Influenza vaccines: a pediatric perspective
1Pediatric Infectious Disease, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA. cmeissner@tufts-nemc.org
Insights
Annual influenza immunization is recommended for children aged 6-59 months and their contacts. This strategy, including a two-dose plan for younger children, aims to reduce disease burden and mortality.
Area of Science:
- Pediatrics
- Infectious Diseases
- Immunology
Background:
- Influenza poses a significant disease burden on children.
- Current immunization recommendations for young children are evolving.
Purpose of the Study:
- To review the disease burden of influenza in children.
- To understand the rationale behind updated immunization recommendations for young children.
- To examine current recommendations for trivalent, inactivated influenza vaccine and live, attenuated influenza vaccine.
Main Methods:
- Review of current scientific literature and public health recommendations regarding influenza vaccination in children.
Main Results:
- Annual influenza immunization is recommended for all children aged 6 to 59 months and their household contacts, starting from the 2006-2007 season.
- A two-dose vaccination strategy is advised for children under 9 years of age.
Conclusions:
- Expanded influenza immunization recommendations are anticipated to decrease outpatient visits, hospitalizations, and mortality rates associated with influenza in both pediatric and adult populations.
Purpose Of Review:
To understand the burden of disease attributable to influenza among children and to understand the basis for changing recommendations for immunization of young children. I will review the current recommendations regarding use of trivalent, inactivated influenza vaccine and live, attenuated influenza vaccine.
Recent Findings:
Annual immunization of all children between 6 and 59 months of age and their household contacts is recommended starting with the 2006-2007 season, including a two-dose strategy for children under 9 years of age.
Summary:
Expanded recommendations are expected to reduce the number of outpatient visits, hospitalization rates and mortality rates due to influenza for both children and adults.
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