[Acute ST-segment elevation also possible in non-coronary disorders]

G A J Jessurun1, F Zijlstra, H J Siebelink

  • 1Universitair Medisch Centrum Groningen, Thoraxcentrum, afd. Cardiologie, Postbus 30.001, 9700 RB Groningen.

Insights

ST-segment elevation on ECG can mimic ST-elevation myocardial infarction (STEMI) but may stem from non-coronary conditions like pericarditis, pneumothorax complications, or sepsis. Careful clinical evaluation is crucial for accurate diagnosis and treatment.

Area of Science:

  • Cardiology
  • Emergency Medicine
  • Diagnostic Imaging

Background:

  • ST-segment elevation myocardial infarction (STEMI) is a critical diagnosis often managed with percutaneous coronary intervention.
  • Electrocardiogram (ECG) changes are pivotal in diagnosing STEMI.
  • Non-coronary conditions can present with ECG findings mimicking STEMI.

Observation:

  • Three patients presented with symptoms suggestive of acute coronary syndrome and ECG findings of ST-segment elevation.
  • Case 1: A young male diagnosed with pericarditis and myocarditis despite normal coronary arteries.
  • Case 2: An elderly female with ST-segment elevation due to chest drain insertion for pneumothorax.
  • Case 3: An ICU patient with ST-segment elevation attributed to sepsis and non-significant coronary artery disease.

Findings:

  • ST-segment elevation on ECG is not exclusive to myocardial infarction.
  • Non-coronary causes, including inflammatory conditions, mechanical pressures, and sepsis, can induce STEMI-like ECG changes.
  • All three patients recovered with appropriate management for their underlying non-coronary conditions.

Implications:

  • Clinicians must consider 'coronary mimicry' when interpreting ST-segment elevation on ECG.
  • A thorough clinical assessment and correlation with patient presentation are essential to differentiate STEMI from non-coronary causes.
  • Over-reliance on ECG findings without clinical context can lead to misdiagnosis and inappropriate treatment.

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