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CYP2D6 polymorphisms in patients with porphyrias

Jimena V Lavandera1, Victoria E Parera, Alcira Batlle

  • 1Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET, Hospital de Clínicas, and Department of Biological Chemistry, Facultad de Ciencias Exactas y Naturales, University of Buenos Aires, Argentina.

Molecular Medicine (Cambridge, Mass.)
|January 18, 2007
PubMed
Summary

Cytochrome P-450 (CYP) gene variations, specifically CYP2D6 polymorphisms, may trigger porphyria disease in patients. Genotyping for CYP2D6 could personalize drug therapy for porphyria patients.

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