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Continuous negative extrathoracic pressure in children after congenital heart surgery
Nobuaki Shime1, Chiaki Toida, Toshiyuki Itoi
1Department of Anesthesiology and Intensive Care, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan. shime@koto.kpu-m.ac.jp
Insights
Continuous negative extrathoracic pressure (CNEP) improved outcomes in children post-congenital heart surgery. This non-invasive ventilation method enhanced oxygenation and reduced cardiac strain, offering a promising management option.
Area of Science:
- Pediatric Cardiology
- Thoracic Surgery
- Critical Care Medicine
Background:
- Congenital heart defects require complex surgical interventions.
- Post-operative management in pediatric intensive care units (PICU) is crucial.
- Optimizing respiratory and hemodynamic support after cardiac surgery is essential.
Purpose of the Study:
- To evaluate the efficacy of continuous negative extrathoracic pressure (CNEP) in pediatric patients following congenital heart defect surgery.
- To assess the impact of CNEP on hemodynamic parameters and gas exchange.
- To determine the safety and potential benefits of prophylactic CNEP use after extubation.
Main Methods:
- A prospective study involving 16 infants and children in the PICU after congenital heart surgery.
- Application of CNEP using a cuirass and ventilator at pressures of -3 to -6 cmH2O.
- Assessment of hemodynamic changes and gas exchange at 1 and 8 hours post-CNEP initiation in spontaneously breathing patients.
Main Results:
- Significant increases in urine output were observed in both groups (49% in Group A, 65% in Group B).
- Central venous pressure decreased, and a trend towards increased arterial blood pressure was noted.
- Oxygen saturation improved significantly in Group B, from 96.5% to 99% at 1 hour and 100% at 8 hours.
Conclusions:
- Prophylactic CNEP post-extubation may reduce right ventricular afterload.
- CNEP appears to improve arterial oxygenation in pediatric cardiac surgery patients.
- CNEP presents a potentially valuable therapeutic option for managing patients after congenital heart surgery.
Objective:
To study the effects of continuous negative extrathoracic pressure (CNEP) in children after surgery for congenital heart defects.
Methods:
We applied - 3 to - 6 cmH2O CNEP with a cuirass and ventilator to 16 infants and children managed in a paediatric intensive care unit after surgery for congenital heart defects between July 2003 and July 2004. Changes in haemodynamics and gas exchange were assessed 1h and 8h after CNEP application. All patients were breathing spontaneously after successful extubation while receiving CNEP.
Results:
Patients were aged 1-34 months (median, 11.5 months). Six had undergone right heart bypass surgery (Group A), and 10 had received positive pressure ventilation for >48 h after other types of heart surgery (Group B). Urine output increased significantly, by 49% at 1 h in Group A, and by 65% in Group B. Decreases in central venous pressure, from median (range) of 15 (12-22)mmHg to 12 (10-21) mmHg in Group A, and from 9 (5-13)mmHg to 8.5 (5-12)mmHg in Group B, and tendency to increases in arterial blood pressure were observed after 1h. In Group B, oxygen saturation increased from 96.5% (84%-100%) at baseline to 99% (87%-100%) and 100% (88%-100%) at 1 h and 8 h, respectively.
Conclusion:
Prophylactic application of CNEP immediately after extubation appears to decrease right ventricular load and improve arterial oxygenation. CNEP might become a useful option in the management of congenital heart surgery patients.
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