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Updated: Jul 17, 2026

13:19
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
[Prostate cancer in Denmark 1943-2002].
Klaus Brasso1, Inga Jona Ingimarsdottir, Lars Thomassen
1Rigshospitalet, Urologisk Afdeling D.
Ugeskrift for Laeger
|January 18, 2007
Summary
Prostate cancer incidence in Denmark has risen significantly since 1943. This increase is likely due to more diagnostic activity, not just screening, necessitating more resources for prostate cancer care.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Context:
- Prostate cancer (PC) incidence and mortality rates have been increasing in Denmark.
- Previous studies could not link rising PC incidence to increased diagnostic procedures.
- This study examines PC incidence and mortality trends in Denmark over a 60-year period (1943-2002).
Purpose:
- To review trends in prostate cancer incidence and mortality rates in Denmark from 1943 to 2002.
- To investigate the drivers behind the observed increases in PC rates.
- To assess the impact of diagnostic policies on PC incidence.
Summary:
- Age-standardized PC incidence in Denmark rose from 11.4/100,000 (1943-47) to 38.2/100,000 (1998-2002).
- Mortality rates increased from 13.5/100,000 (1953) to 19.1/100,000 (1993-98).
- Recent increases in incidence, particularly in younger patients, suggest a shift towards more active diagnostic policies, possibly due to unsystematic PSA-based screening.
Impact:
- The findings highlight a growing prostate cancer incidence in Denmark, with recent trends likely driven by increased diagnostic activity.
- This rise contrasts with national screening recommendations and necessitates increased resource allocation for PC evaluation, treatment, and follow-up.
- Understanding these trends is crucial for effective public health strategies and resource management in oncology.
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