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Updated: Jul 17, 2026
06:35
Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test
Published on: April 27, 2016
Vascular endothelium summary statement II: Cardiovascular disease prevention and control
George A Mensah1, Una S Ryan, W Craig Hooper
1National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, (CDC), Mailstop K-40, 4770 Buford Highway NE, Atlanta, GA 30341-3717, USA. GMensah@cdc.gov
Vascular Pharmacology
|January 19, 2007
Summary
Cardiovascular disease (CVD) prevention hinges on managing modifiable risk factors that impair endothelial function. Preserving endothelial health is key to reducing heart disease and stroke incidence.
Area of Science:
- Cardiovascular disease research
- Endothelial function and dysfunction
- Public health challenges
Background:
- Cardiovascular disease (CVD), including ischemic heart disease and stroke, is a leading global cause of morbidity and mortality.
- Established modifiable CVD risk factors are known to induce endothelial activation and dysfunction.
- Preserving endothelial function is linked to reduced CVD risk.
Framework:
- Understanding the science of endothelial dysfunction in CVD pathogenesis.
- Evaluating diagnostic methods for endothelial dysfunction.
- Developing strategies to enhance endothelial resilience.
Implementation:
- Focusing on prevention and control of major modifiable CVD risk factors.
- Implementing public health strategies that support endothelial health.
- Translating research findings into clinical practice.
Implications:
- Improved understanding of endothelial dysfunction can refine CVD prevention.
- Enhanced endothelial resilience may offer new therapeutic targets.
- Advances in preserving endothelial function are crucial for reducing the global burden of CVD.
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