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[Case of severe ulcerative colitis successfully treated with intravenous cyclosporine without high dose

Daisuke Kubota1, Takanori Kanai, Fumiro Yui

  • 1Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Japan.

Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-Enterology
|January 19, 2007
PubMed

A 44-year-old women developed marked myopathy one year earlier, when she was treated with intravenous prednisolone for acute severe exacerbation of ulcerative colitis. When she was admitted to our hospital for another severe exacerbation, intravenous cyclosporine A was administered as monotherapy because she could not tolerate corticosteroid. The treatment was successful and she obtained complete remission. Cyclosporine A monotherapy is considered to be a valuable alternative to proctocolectomy for severe ulcerative colitis patients who cannot tolerate corticosteroid.

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