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Updated: Jul 17, 2026
09:34
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
Educating health-care professionals about genetics and genomics
Alan E Guttmacher1, Mary E Porteous, Joseph D McInerney
1National Human Genome Research Institute, Building 31, Room 4B09, Bethesda, MD 20892-2152, USA. guttmach@mail.nih.gov
Nature Reviews. Genetics
|January 19, 2007
Summary
The genome era has transformed biomedical research but not yet clinical practice. Improving healthcare providers' genomic literacy is essential for integrating genomic medicine into patient care.
Area of Science:
- Genomics and Genomic Medicine
- Biomedical Research
- Clinical Practice
Background:
- The 'genome era' has revolutionized biomedical research through advances in genetics and genomics.
- Despite research impact, the genome era has not significantly reached most clinicians.
- Genomic medicine requires a shift from research applications to clinical integration.
Approach:
- Describe the necessary knowledge, skills, and attitudes for genomic medicine.
- Outline strategies for integrating genomic medicine education into the healthcare community.
- Focus on bridging the gap between genomic research and clinical application.
Key Points:
- Genomic advances include human genome sequencing, haplotype mapping, open-access databases, and cost-effective genotyping.
- Genomic literacy among healthcare providers is crucial for clinical adoption.
- Successful integration necessitates specific educational and attitudinal changes.
Conclusions:
- Genomic medicine's clinical impact hinges on enhanced genomic literacy in healthcare professionals.
- Integrating genomic knowledge into clinical practice requires targeted educational approaches.
- The transition necessitates a proactive strategy to prepare the healthcare community for genomic medicine.
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