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Experience with chronic peritoneal dialysis in infants
1Division of Pediatric Nephrology, Hospital for Sick Children, University of Toronto, Ont., Canada.
Insights
Chronic peritoneal dialysis is a viable infant dialysis option. While it improves weight, infants experienced poor linear growth, developmental delays, and altered biochemical levels.
Area of Science:
- Pediatrics
- Nephrology
- Infant Health
Background:
- Infantile chronic kidney disease necessitates renal replacement therapy.
- Peritoneal dialysis is an established treatment for pediatric end-stage renal disease.
Purpose of the Study:
- To evaluate the efficacy and outcomes of chronic peritoneal dialysis in infants.
- To analyze growth and biochemical parameters in infants undergoing peritoneal dialysis.
Main Methods:
- Retrospective analysis of 17 infants (14 boys, 3 girls) aged 2.7-22.5 months.
- Patients underwent continuous ambulatory peritoneal dialysis (CAPD) and/or continuous cycling peritoneal dialysis (CCPD).
- Growth and biochemical data were collected and analyzed.
Main Results:
- Poor linear growth was observed despite adequate weight gain.
- A high incidence of developmental delay was noted.
- Biochemical abnormalities included lower plasma albumin, phosphate, and sodium, with elevated cholesterol and triglycerides.
Conclusions:
- Chronic peritoneal dialysis is a feasible and effective dialysis modality for infants.
- Careful monitoring of growth and biochemical parameters is crucial for infants on chronic peritoneal dialysis.
Abstract:
We describe our experience with chronic peritoneal dialysis in 17 infants. Fourteen boys and 3 girls, aged 2.7-22.5 months, were on continuous ambulatory peritoneal dialysis (CAPD) for 215.1 months with 5 infants on continuous cycling peritoneal dialysis (CCPD) for 71.2 months subsequently. Analysis of growth and biochemical data on 16 CAPD and 5 CCPD patients showed poor linear growth despite improved weight gain, high incidence of developmental delay, tendency to lower plasma albumin, phosphate and sodium and increased plasma cholesterol and triglyceride levels. Overall chronic peritoneal dialysis proved to be a possible and effective means of dialysis in infants.