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Experience with chronic peritoneal dialysis in infants
1Division of Pediatric Nephrology, Hospital for Sick Children, University of Toronto, Ont., Canada.
Child Nephrology and Urology
|January 1, 1991
Summary
Chronic peritoneal dialysis is a viable infant dialysis option. While it improves weight, infants experienced poor linear growth, developmental delays, and altered biochemical levels.
Area of Science:
- Pediatrics
- Nephrology
- Infant Health
Background:
- Infantile chronic kidney disease necessitates renal replacement therapy.
- Peritoneal dialysis is an established treatment for pediatric end-stage renal disease.
Purpose of the Study:
- To evaluate the efficacy and outcomes of chronic peritoneal dialysis in infants.
- To analyze growth and biochemical parameters in infants undergoing peritoneal dialysis.
Main Methods:
- Retrospective analysis of 17 infants (14 boys, 3 girls) aged 2.7-22.5 months.
- Patients underwent continuous ambulatory peritoneal dialysis (CAPD) and/or continuous cycling peritoneal dialysis (CCPD).
- Growth and biochemical data were collected and analyzed.
Main Results:
- Poor linear growth was observed despite adequate weight gain.
- A high incidence of developmental delay was noted.
- Biochemical abnormalities included lower plasma albumin, phosphate, and sodium, with elevated cholesterol and triglycerides.
Conclusions:
- Chronic peritoneal dialysis is a feasible and effective dialysis modality for infants.
- Careful monitoring of growth and biochemical parameters is crucial for infants on chronic peritoneal dialysis.