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Updated: Jul 17, 2026
09:37
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
MutationView/KMcancerDB: a database for cancer gene mutations.
Nobuyoshi Shimizu1, Masafumi Ohtsubo, Shinsei Minoshima
1Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan. shimizu@dmb.med.keio.ac.jp
Cancer Science
|January 20, 2007
Summary
Cancer arises from accumulated gene mutations impacting protein function. This study introduces KMcancerDB, a user-friendly database for cancer gene mutation data, aiding diagnosis and drug discovery.
Area of Science:
- Genetics
- Bioinformatics
- Cancer Research
Background:
- Cancer develops due to accumulated genetic mutations affecting cellular functions.
- Understanding these mutations is crucial for cancer diagnosis and developing targeted therapies.
- Existing databases offer molecular information on cancer-related genes.
Purpose of the Study:
- To review existing cancer gene databases.
- To introduce the user-friendly KMcancerDB database.
- To detail the features and capabilities of MutationView/KMcancerDB.
Main Methods:
- Literature review of cancer gene databases.
- Development and description of the KMcancerDB database.
- Utilizing graphic display and sophisticated search functions.
Main Results:
- KMcancerDB, derived from MutationView, contains data for 42 cancer-related genes.
- The database offers a user-friendly interface with advanced graphic display.
- A sophisticated, single-URL search function is provided for all genes.
Conclusions:
- KMcancerDB enhances accessibility to cancer gene mutation data.
- The database facilitates research in cancer mechanisms, diagnosis, and drug discovery.
- User-friendly features improve the utility of cancer genetic information resources.
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