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Related Experiment Video

Updated: Jul 17, 2026

Identification and Dissection of Diverse Mouse Adipose Depots

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

[Adipose tissue and adipokines].

Joana V Costa¹, João S Duarte

¹Serviço de Endocrinologia, Hospital Egas Moniz, Lisboa, Portugal.

Acta Medica Portuguesa

|January 20, 2007

Summary

Adipose tissue produces adipokines with immunologic, cardiovascular, metabolic, and endocrine functions. Further research is needed to clarify mechanisms and clinical applications for obesity-related dysfunction.

Area of Science:

Adipose tissue as an endocrine organ.
Diverse roles of adipokines.

Context:

Obesity is linked to cardiovascular risk.
Adipose tissue regulates lipid and glucose metabolism.
Adipose tissue influences energy homeostasis.

Purpose:

To categorize adipokines based on their primary functions.
To highlight key adipokines in inflammation, cardiovascular health, metabolism, and endocrine signaling.
To underscore the need for further research into adipokine mechanisms and clinical applications.

Summary:

Adipokines are grouped into immunologic (e.g., Interleukin-6, Tumor Necrosis Factor-alpha), cardiovascular (e.g., renin-angiotensin axis molecules, plasminogen activator inhibitor-I), metabolic (e.g., adiponectin, resistin, visfatin), and endocrine (e.g., leptin) categories.

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Identification and Dissection of Diverse Mouse Adipose Depots

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Adipose tissue plays crucial roles in inflammation, cardiovascular risk, and metabolic regulation, including lipid and glucose homeostasis.

Leptin exemplifies the endocrine function of adipose tissue in regulating energy storage and fertility.

Impact:

Enhanced understanding of adipose tissue's endocrine role.
Potential for novel therapeutic targets for obesity-related cardiovascular and metabolic dysfunction.
Improved strategies for managing obesity-associated morbidity and mortality.