Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report.

Oncology letters·2026
Same author

Desipramine treatment disrupts phagocytic and intracellular survival of <i>Brucella abortus</i> 544 in RAW 264.7 cells and promotes bacterial resistance with enhanced immune responses in ICR mice.

Frontiers in veterinary science·2026
Same author

Analysis of the Frequency and Associated Factors of Skin Toxicity in Patients Receiving Ribociclib-Based Therapy for Metastatic Breast Cancer.

Cancers·2026
Same author

Interreader Agreement for Individual Ancillary Features in LI-RADS CT/MRI Version 2018: A Systematic Review and Meta-Analysis.

AJR. American journal of roentgenology·2026
Same author

Hepatectomy for Hepatocellular Carcinoma in Elderly Patients: Perioperative Outcomes in the Modern Minimally Invasive Era.

Journal of clinical medicine·2026
Same author

Clinicopathological Spectrum of EBV-Related Primary Splenic Tumors Identified by Splenectomy: A Case Series.

Diagnostics (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jul 17, 2026

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration
08:33

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration

Published on: August 7, 2019

Scrub typhus: clinical, pathologic, and imaging findings.

Yeon Joo Jeong1, Suk Kim, Yeh Dae Wook

  • 1Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, 1-10 Ami-Dong, Seo-gu, Pusan 602-739, Republic of Korea.

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|January 20, 2007
PubMed
Summary

Scrub typhus, an acute febrile illness caused by Orientia tsutsugamushi, involves vasculitis affecting multiple organs. Early diagnosis through clinical suspicion and recognizing radiologic signs is crucial for reducing patient morbidity.

Related Experiment Videos

Last Updated: Jul 17, 2026

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration
08:33

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration

Published on: August 7, 2019

Area of Science:

  • Infectious Diseases
  • Pathology
  • Internal Medicine

Background:

  • Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi.
  • The primary pathology involves focal or disseminated vasculitis due to endothelial cell destruction and leukocyte infiltration.

Purpose of the Study:

  • To summarize the key pathological changes, diagnostic approaches, and clinical manifestations of scrub typhus.
  • To emphasize the importance of early diagnosis and treatment in managing scrub typhus.

Main Methods:

  • Review of clinical features, diagnostic methods (history, clinical exam, serology), and common organ involvements.
  • Analysis of pathological changes, including vasculitis and its impact on pulmonary, abdominal, and central nervous systems.

Main Results:

  • Common findings include lymphadenopathy, pulmonary manifestations (pneumonia, edema, hemorrhage), and abdominal signs (splenomegaly, gallbladder wall thickening).
  • Central nervous system involvement, such as meningoencephalitis, is nearly universal.
  • Diagnosis relies on exposure history, clinical presentation, and serologic tests.

Conclusions:

  • Scrub typhus presents with diverse clinical and radiologic manifestations, often involving vasculitis.
  • High clinical suspicion and familiarity with its manifestations are essential for early diagnosis.
  • Timely treatment initiated upon early diagnosis can significantly reduce patient morbidity.