Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Symptomatic REM sleep behaviour disorder.

A Thomas1, L Bonanni, M Onofrj

  • 1Neurophysiopathology, Movement Disorders Center, University "G. D'Annunzio" Chieti and Pescara, Italy, Via Fonte Romane, I-65124, Pescara, Italy, onofrj@unich.it.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|January 20, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.

The Journal of biological chemistry·2001
Same author

Somatostatin, its receptors and analogs, in lung cancer.

Chemotherapy·2001
Same author

[A study on abnormal chondrocyte differentiation and abnormal expression of collagen types in articular cartilage from patients with Kaschin-Beck disease].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2001
Same author

Improved flow cytometric detection of HLA alloantibodies using pronase: potential implications in renal transplantation.

Transplantation·2001
Same author

Rapid detection of resistance to rifampicin in Mycobacterium leprae.

Leprosy review·2001
Same author

Status of long absentees among multibacillary leprosy patients admitted to a controlled clinical study.

Indian journal of leprosy·2001
Same journal

Early and severe masticatory muscle involvement in SOD1-ALS: a case report with biomarker-clinical dissociation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Early multimodal predictors of good neurological outcome in comatose patients after cardiac arrest: a prospective single-center cohort study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Telemedicine for headache disorders in real-world practice: from patient experience to health system impact.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Topography and functional connectivity analysis of heart surgery-associated brain lesions: a literature review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Limb apraxia in Parkinson's disease and atypical parkinsonian syndromes: a systematic review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Primary Sjogren syndrome with suspected central nervous system inflammatory involvement.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
See all related articles

Rapid eye movement (REM) sleep behaviour disorder (RBD) is linked to neurodegenerative diseases like Parkinson's and Alzheimer's. This review explores symptomatic RBD and drug-induced cases, discussing diagnostic challenges and potential causes.

Area of Science:

  • Neurology
  • Sleep Medicine
  • Neurodegenerative Disorders

Background:

  • Rapid eye movement (REM) sleep behaviour disorder (RBD) is a recognized prodromal or concomitant symptom in various neurodegenerative conditions.
  • Prevalence of RBD differs significantly across synucleinopathies (19-77%) and tauopathies (0-27%).
  • RBD is also observed in other neurological and psychiatric conditions, including ALS, epilepsy, and PTSD.

Purpose of the Study:

  • To review the current literature on symptomatic RBD.
  • To examine drug-induced RBD, including antidepressants and other medications.
  • To discuss controversial findings, classification issues, and hypothetical etiological mechanisms of RBD.

Main Methods:

  • Literature review of symptomatic and drug-induced RBD.

Related Experiment Videos

  • Analysis of prevalence data in synucleinopathies and tauopathies.
  • Discussion of etiological hypotheses and diagnostic challenges.

    • Main Results:

    • RBD is highly prevalent in synucleinopathies but rare in tauopathies.
    • Certain medications, particularly antidepressants, are frequently implicated in precipitating RBD.
    • Significant variability exists in reported RBD prevalence and diagnostic criteria.

    Conclusions:

    • RBD serves as a crucial clinical marker for underlying neurodegenerative processes.
    • Medication-induced RBD highlights the complex interplay between drugs and sleep-wake regulation.
    • Further research is needed to clarify RBD's etiology and refine diagnostic approaches.