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Release of soluble E-selectin from activated endothelial cells upon apoptosis

Elizabeth O Harrington1, Tihomir Stefanec, Julie Newton

  • 1Vascular Research Laboratory, Providence Veterans Affairs Medical Center, Department of Medicine, Brown Medical School, Providence, Rhode Island 02908, USA. Elizabeth_Harrington@brown.edu

Lung
|January 20, 2007
PubMed

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Phagocytosis of Apoptotic Cells

Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or  immature dendritic cells. Non-professional phagocytes such as  epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes. 
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