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A New Oleanic Acid Derivative from Securinega tinctoria.

L M Carvalho¹, J Seita

¹Department of Chemistry, University of Tras-os-Montes and Alto Douro, 5000 Vila Real, Portugal.

|August 1, 1993

Summary

Researchers identified a new oleanolic acid derivative from the stems of SECURINEGA TINCTORIA. This triterpenoid, alongside beta-sitosterol beta-D-glucopyranoside, expands our knowledge of plant-derived compounds.

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Area of Science:

Phytochemistry
Natural Product Chemistry
Organic Chemistry

Background:

Securinega tinctoria is a plant species known for its diverse chemical constituents.
Triterpenoids are a class of naturally occurring compounds with various biological activities.
Previous phytochemical investigations of Securinega tinctoria have identified several compounds.

Purpose of the Study:

To isolate and characterize the triterpenoid constituents from the stems of Securinega tinctoria.
To identify novel compounds with potential therapeutic applications.
To contribute to the understanding of the phytochemical profile of Securinega tinctoria.

Main Methods:

Defatting of plant material to remove lipids.
Extraction using chloroform solvent.
Chromatographic separation techniques (e.g., column chromatography).
Spectroscopic analysis (e.g., NMR, Mass Spectrometry) for structural elucidation.

Main Results:

Isolation of beta-sitosterol beta-D-glucopyranoside.
Identification of a new oleanolic acid derivative: 3beta(P-hydroxy-trans-cinnamoyloxy)olean-12-en-28-oic acid.
The new compound is a triterpenoid ester.

Conclusions:

The study successfully isolated and identified a novel oleanolic acid derivative from Securinega tinctoria stems.
The findings expand the known phytochemical diversity of the Securinega genus.
This new triterpenoid may serve as a lead compound for future pharmacological studies.