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Published on: August 16, 2018
A New Triterpenoidal from Vernonia cinerea
T N Misra1, R S Singh, R Srivastava
1Natural Products Research Laboratory, Department of Chemistry, University of Gorakhpur, Gorakhpur-273009 (U.P.), India.
Planta Medica
|October 1, 1993
Summary
Researchers isolated a new triterpenoid, 3beta-acetoxyurs-19-ene, and lupeol acetate from Vernonia cinerea roots. Spectral analyses confirmed their structures, advancing phytochemical knowledge.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
- Organic Chemistry
Background:
- Vernonia cinerea (Compositae) is a plant species with potential medicinal properties.
- Triterpenoids are a class of organic compounds found in plants, often exhibiting biological activity.
Purpose of the Study:
- To isolate and characterize novel compounds from the roots of Vernonia cinerea.
- To identify specific triterpenoids present in the plant's root extract.
Main Methods:
- Extraction of compounds from Vernonia cinerea roots.
- Isolation of individual chemical constituents.
- Structure elucidation using spectral analysis techniques (e.g., NMR, Mass Spectrometry).
Main Results:
- A new triterpenoid, identified as 3beta-acetoxyurs-19-ene (compound 1), was successfully isolated.
- Lupeol acetate was also identified as a constituent of the plant roots.
- The structures of the isolated compounds were confirmed through comprehensive spectral data interpretation.
Conclusions:
- The study successfully identified two triterpenoids from Vernonia cinerea roots, including a novel compound.
- This research contributes to the understanding of the phytochemical profile of Vernonia cinerea.
- The findings may provide a basis for further investigation into the biological activities of these compounds.
