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Infectious muscle disease.

I Parasca1, Laura Damian, Adriana Albu

  • 1Medical Clinic II, "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. parasca@yahoo.com

Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne
|January 24, 2007
PubMed
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Infectious muscle diseases stem from diverse causes, including viral, bacterial, and parasitic infections. Diagnosis relies on clinical evidence and imaging, with treatment involving antibiotics and surgery.

Area of Science:

  • Infectious Diseases
  • Musculoskeletal System Infections
  • Medical Microbiology

Background:

  • Infectious muscle diseases present with varied etiologies, including viral myositides (Influenza, Coxsackie, HIV).
  • Bacterial myositis, once considered tropical, is now prevalent globally due to migration and AIDS.
  • Tuberculosis, particularly osteoarticular forms, is endemic in regions like Central-Eastern Europe.

Purpose of the Study:

  • To review the diverse etiologies of infectious muscle diseases.
  • To highlight diagnostic approaches, including imaging techniques.
  • To outline current management strategies for musculoskeletal infections.

Main Methods:

  • Review of clinical and laboratory evidence for viral myositides.
  • Discussion of bacterial infections (e.g., psoas abscess, streptococcal infections, Koch bacillus).

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  • Inclusion of parasitic etiologies (e.g., Trichinella, Toxoplasma) and rare conditions (e.g., gas gangrene).

    • Main Results:

    • Viral myositides are confirmed by clinical and lab findings.
    • Bacterial myositis is a growing concern in developed nations.
    • Parasitic infections and rare anaerobic myonecrosis also contribute to musculoskeletal infections.
    • Imaging methods like ultrasonography and CT are crucial for diagnosis, with MRI for axial skeleton involvement.

    Conclusions:

    • Infectious muscle diseases require a comprehensive diagnostic approach.
    • Management hinges on prompt antibiotic therapy and surgical intervention when necessary.
    • Immune status significantly influences susceptibility and presentation of these infections.