Related Experiment Video
Updated: Jul 17, 2026

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
Medical care and alcohol use after testing hepatitis C antibody positive at STD clinic and HIV test site screening
Karen E Mark1, Paula J Murray, David B Callahan
1Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA. kmark@u.washington.edu
Insights
Public screening for hepatitis C virus (HCV) identified many antibody-positive individuals. However, only half received medical evaluation, highlighting a need to improve access to care for HCV screening program participants.
Area of Science:
- Public health
- Infectious disease epidemiology
- Hepatitis C virus (HCV) screening
Background:
- Hepatitis C virus (HCV) screening is recommended for at-risk populations by the CDC.
- Limited data exist on outcomes for individuals testing antibody to HCV (anti-HCV) positive through screening.
- Understanding post-screening care is crucial for effective public health interventions.
Purpose of the Study:
- To assess medical evaluation and HCV treatment rates among anti-HCV positive individuals identified via public screening.
- To examine changes in alcohol consumption post-diagnosis.
- To identify barriers to medical care access for anti-HCV positive individuals.
Main Methods:
- Anti-HCV positive individuals from STD clinics and an HIV test site were identified.
- Participants received education and referral for positive test results.
- Follow-up contact via telephone occurred at 3, 6, and >=12 months post-diagnosis.
Main Results:
- Of 286 contacted individuals, 55% received a medical evaluation, and 12% initiated HCV treatment.
- Among those who drank alcohol, 76% reduced consumption after diagnosis.
- Lack of medical insurance was the primary barrier to medical evaluation.
Conclusions:
- Public HCV screening identifies individuals, but medical evaluation rates remain suboptimal.
- Reduced alcohol consumption is a positive outcome, but access to care is a significant challenge.
- Improving medical access for anti-HCV positive individuals is essential to enhance screening program effectiveness.
Objectives:
The Centers for Disease Control and Prevention recommend screening individuals at risk for hepatitis C virus (HCV) infection. However, few published data describe outcomes of individuals with antibody to HCV (anti-HCV) identified through screening programs. The purpose of this study was to assess rates of medical evaluation and HCV treatment, change in alcohol consumption, and barriers to medical care after testing anti-HCV positive through a public screening program.
Methods:
Anti-HCV positive individuals identified through San Diego sexually transmitted disease (STD) clinics and an HIV test site screening program were informed of positive test results, provided education and referral, and contacted by telephone three, six, and > or =12 months later.
Results:
From September 1, 1999, to December 31, 2001, 411 anti-HCV positive individuals were newly identified, of whom 286 (70%) could be contacted > or = three months after receipt of test results (median length [range] of follow-up 14 [3-35] months). Of these 286, 156 (55%) reported having received a medical evaluation, of whom 19 (12%) began HCV treatment. Of 132 who reported drinking alcohol before diagnosis, 100 (76%) reported drinking less after diagnosis. Individuals with medical insurance at diagnosis were more likely than those without insurance to obtain a medical evaluation during follow-up (75 [68%] of 111 vs. 70 [45%] of 155; p < 0.001). Among those who did not obtain an evaluation, the most commonly reported reason was lack of insurance.
Conclusions:
Only about half of newly identified anti-HCV positive individuals received a medical evaluation, although 76% reported drinking less alcohol. Identifying ways to improve medical access for those who are anti-HCV positive could improve the effectiveness of screening programs.
Related Concept Videos
Hepatitis
Sexually Transmitted Infections
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Preventive Healthcare Services
Genital Herpes
Viral Hepatitis I: Introduction