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Updated: Jul 17, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Off-pump coronary artery bypass surgery in a renal transplant patient
Koji Hattori1, Ryo Hoshino, Masato Tochii
1Department of Cardiovascular Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan. hattori@fujita-hu.ac.jp
Insights
Off-pump coronary artery bypass grafting is a rare procedure for renal transplant patients. This case study shows successful emergency surgery for unstable angina in a kidney transplant recipient, with good long-term outcomes.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Transplantation Medicine
Background:
- Off-pump coronary artery bypass grafting (OPCAB) is infrequently performed in renal transplant recipients.
- Coronary artery disease poses a significant risk in patients with end-stage renal disease and post-transplant complications.
Observation:
- A 59-year-old male renal transplant recipient presented with unstable angina pectoris.
- Coronary angiography identified severe triple-vessel disease, necessitating urgent intervention.
- The patient underwent emergency off-pump coronary artery bypass grafting with intraaortic balloon pumping support.
Findings:
- Complete revascularization was achieved successfully using OPCAB.
- The patient's hemodynamic status remained stable postoperatively, allowing for early cessation of intraaortic balloon pumping.
- Immunosuppressive therapy was managed without compromising cardiac surgical recovery or renal function.
Implications:
- This case demonstrates the feasibility and safety of emergency OPCAB in selected renal transplant recipients with severe coronary artery disease.
- Successful surgical management can improve angina symptoms and long-term prognosis in this high-risk patient population.
- Careful perioperative management, including immunosuppression, is crucial for optimal outcomes in combined cardiac and transplant surgery.
Abstract:
Off-pump coronary artery bypass grafting is rarely applied to patients who have previously received a renal transplant in Japan. A 59-year-old male renal transplant recipient was admitted for unstable angina pectoris. Emergency coronary angiography revealed triple-vessel disease. Intraaortic balloon pumping was applied, followed by emergency off-pump coronary bypass grafting for complete revascularization. Intraaortic balloon pumping was ceased immediately after the operation because his hemodynamic status was stable. On the morning of the surgery, the patient was given his standard dose of immunosuppressive agents. On postoperative day 1, he was extubated and infused with immunosuppressive agents. On postoperative day 2, his usual immunosuppressive agents were resumed as per his normal dosage. He recovered uneventfully and is well without angina pectoris and renal complication 1 year after the operation.
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