Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Mutagenicity and Carcinogenicity01:25

Mutagenicity and Carcinogenicity

Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Economic evaluation of adjuvant chemotherapy for non-metastatic sarcoma using the real-world data from the French nationwide DEEPSARC study.

Journal of medical economics·2026
Same author

Hyperprogression after Immune Checkpoint Inhibitors: A Cloudy Phenomenon with Real-life Consequences.

Cancer communications (London, England)·2026
Same author

Overall survival of patients with localized soft tissue sarcoma treated with or without adjuvant chemotherapy (DEEPSARC): a real world nationwide retrospective cohort study in France.

EClinicalMedicine·2026
Same author

Characteristics and outcome of intra-abdominal desmoid-type fibromatosis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Natural history and treatment sensitivity of alveolar soft part sarcoma: A national multicenter analysis from the French sarcoma group.

European journal of cancer (Oxford, England : 1990)·2026
Same author

[Sarcoma: a plural entity].

La Revue du praticien·2026

Related Experiment Video

Updated: Jul 17, 2026

Assessing Cytotoxicity of Metabolites of Typical Triazole Pesticides in Plants
08:22

Assessing Cytotoxicity of Metabolites of Typical Triazole Pesticides in Plants

Published on: December 22, 2023

[Cancers and pesticides: current data].

Nicolas Penel1, Damien Vansteene

  • 1Département de cancérologie générale, Centre Oscar-Lambret, 3, rue Frédéric-Combemale, 59020, Lille. penel@o-lambret.fr

Bulletin Du Cancer
|January 24, 2007
PubMed
Summary

Occupational pesticide exposure is linked to increased risks of certain cancers, including non-Hodgkin's lymphoma and childhood cancers. Future studies need toxicological analysis to accurately measure pesticide exposure and confirm these links.

More Related Videos

Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat
06:11

Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat

Published on: April 28, 2023

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Related Experiment Videos

Last Updated: Jul 17, 2026

Assessing Cytotoxicity of Metabolites of Typical Triazole Pesticides in Plants
08:22

Assessing Cytotoxicity of Metabolites of Typical Triazole Pesticides in Plants

Published on: December 22, 2023

Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat
06:11

Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat

Published on: April 28, 2023

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Area of Science:

  • Environmental Health
  • Epidemiology
  • Toxicology

Context:

  • Pesticide use is widespread, leading to potential occupational and parental exposure.
  • Existing epidemiological studies on pesticide exposure and cancer risk often lack conclusive evidence due to measurement difficulties.
  • Increased incidence of childhood cancers has been suggested in relation to parental pesticide exposure.

Purpose:

  • To review the link between pesticide exposure and cancer risk.
  • To highlight the challenges in accurately measuring pesticide exposure in epidemiological studies.
  • To propose the inclusion of toxicological analyses in future research.

Summary:

  • Pesticide exposure is associated with elevated risks for non-Hodgkin's lymphoma, hairy cell leukemia, and childhood cancers.
  • Current epidemiological data is often inconclusive because of the difficulty in quantifying pesticide exposure levels.
  • Incorporating toxicological assessments into future studies is recommended for more precise exposure measurement.

Impact:

  • Highlights the need for improved methodologies in environmental health research.
  • Underscores the potential public health risks associated with pesticide exposure.
  • Informs future research directions for cancer epidemiology and toxicology.