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Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity
F J Martinez-Guijarro1, E Soriano, J A Del Rio
1Catedra de Citologia e Histologia, Facultad de Ciencias Biologicas, Universidad de Valencia, Burjasot, Spain.
Abstract:
Zinc-positive boutons, originating in the medial cortex of lizards, exhibit glutamate immunoreactivity. This finding supports the presumed homology between lizard zinc-positive boutons and the hippocampal mossy fibres of mammals, which are also glutamate-immunoreactive and zinc-positive. Zinc-positive boutons of lizards contain a chelatable pool of zinc located in the hippocampal mossy fibres of mammals. These synaptic systems also contain glutamate, which indicates a possible simultaneous action of zinc and glutamate during synaptic transmission.
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