Related Experiment Video
Updated: Jul 17, 2026
08:47
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Sweat test in asthmatic children; a single center study
Bahram Mirsaeid Ghazi1, Roya Khalesi, Mohsen Naseri
1Department of Pediatrics, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. bahrami_ch@yahoo.com
Iranian Journal of Allergy, Asthma, and Immunology
|January 24, 2007
Summary
A positive sweat test, indicating Cystic Fibrosis (CF), was found in 26% of asthmatic children. This suggests screening asthmatic children with specific symptoms for CF is crucial.
Area of Science:
- Pediatrics
- Pulmonology
- Genetics
Background:
- Asthma and Cystic Fibrosis (CF) share overlapping clinical manifestations.
- The diagnostic utility of sweat testing in asthmatic children requires further investigation.
Purpose of the Study:
- To determine the frequency of positive sweat tests in pediatric asthma patients.
- To identify clinical indicators associated with a positive sweat test in this cohort.
Main Methods:
- A cross-sectional study involving 135 asthmatic children at Bahrami Children Hospital, Tehran.
- All participants underwent sweat testing.
- Data collection included clinical signs, symptoms, and asthma duration.
Main Results:
- A positive sweat test was observed in 26% (35/135) of asthmatic children.
- Positive sweat tests correlated significantly with recurrent respiratory infections, chronic diarrhea, and failure to thrive.
- Children with positive tests had a longer mean asthma duration (49.3 months) compared to those with negative tests (18.1 months).
Conclusions:
- The sweat test is a valuable screening tool for Cystic Fibrosis in asthmatic children presenting with specific symptoms.
- Consider sweat testing for asthmatic children with recurrent respiratory infections, chronic diarrhea, failure to thrive, and prolonged asthma duration.
Related Concept Videos
01:30Asthma-IV: Diagnostic and Management
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
01:13Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
01:24Asthma-III: Symptoms and Complications
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
01:29Asthma-I: Introduction
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
01:28Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
01:26Asthma-II: Pathophysiology and Classification
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include: