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Published on: February 8, 2020
[Wilms' tumors in adults]
1Urologische Klinik mit Poliklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054, Erlangen. vahudin.zugor@uro.imed.uni-erlangen.de
Der Urologe. Ausg. A
|January 24, 2007
Summary
Adult Wilms tumors, rare in adults, originate from primitive stem cells. This study details two adult cases, highlighting the need for more research into adult Wilms tumor biology and treatment.
Area of Science:
- Pediatric Oncology
- Adult Oncology
- Nephrology
Background:
- Wilms tumors are rare in adults, with unknown etiology and biology.
- They arise from persistent, primitive metanephrogenic stem cells.
- Adult incidence is approximately 0.2 per million in Europe and the USA.
Observation:
- This study presents two adult patients with Wilms tumors.
- Both patients had histologically confirmed diagnoses.
- Treatment involved radical nephrectomy and chemotherapy.
Findings:
- The study describes the clinical course of Wilms tumors in two adult patients.
- Management followed the SIOP nephroblastoma study protocols.
- Detailed case information contributes to understanding adult Wilms tumor progression.
Implications:
- Highlights the rarity and limited research on adult Wilms tumors.
- Case reports like this are crucial for advancing knowledge in adult nephroblastoma.
- Emphasizes the need for further investigation into adult Wilms tumor pathogenesis and therapeutic strategies.
