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[The standardization of colloid osmotic pressure of blood substitutes with a perfluorocarbon base]
J Draffehn1, H Reichelt, S Sauer
1Interdisziplinäre Arbeitsgruppe Blutersatzmittel, Militärmedizinische Akademie Bad Saarow.
Abstract:
Besides a number of other characteristic features the colloidal osmotic pressure of blood substitutes is of importance, since it regulates the physiological balance between the intra- and extravascular fluid content. The colloidal osmotic pressure in blood is determined predominantly by the albumin fraction. The entropy increase on diluting albumin which, can't pass semipermeable vascular walls of the intravascular substances are used in blood substitutes to maintain the colloidal osmotic pressure. Their selection and appropriate are of great importance for the efficiency of blood substitutes.
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