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On the superposition of currents from ion channels
1Department of Physics, University of California, San Diego, La Jolla 92093.
Abstract:
We derive a number of statistical properties of the superposition of several independent channels contributing to a patch-clamp recording. Failure of these properties indicates dependence of the channels and may suggest the nature of interactions. We show how properties such as dwell-time distributions of the individual channels may be determined from those of the superposition in the case that the channels are independent.