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Preparation of cross-linked poly[(epsilon-caprolactone)-co-lactide] and biocompatibility studies for tissue
Hiroshi Miyasako1, Kazuya Yamamoto, Aiko Nakao
1Department of Nanostructure and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima 890-0065, Japan.
Abstract:
In this study, cross-linked materials were prepared using the branched macromonomer with different CL/LA molar ratios, and feasibility studies for tissue engineering were carried out. The thermal and mechanical properties of these materials depended on the CL/LA compositions; however, there was no change in the wettability of each material. The HeLa cells adhesion and growth on the CL-LA7030c were equal to that on the commercially available polystyrene dish. The protein absorption experiment using the FBS proteins revealed that the materials with well-grown cells showed better adhesion of the proteins. [photo: see text]
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