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Related Concept Videos

Drug Nomenclature01:17

Drug Nomenclature

During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that the same...
Drug Classes and Categories01:25

Drug Classes and Categories

Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
Pharmaceutical Equivalents01:26

Pharmaceutical Equivalents

As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
Clinically Relevant Drug Product Specifications: Methods of Establishment01:29

Clinically Relevant Drug Product Specifications: Methods of Establishment

Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
How Data are Classified: Categorical Data01:11

How Data are Classified: Categorical Data

A variable, usually notated by capital letters such as X and Y, is a characteristic or measurement that can be determined for each member of a population. Data are the actual values of variables. They may be numbers, or they may be words. Datum is a single value.
Data are classified based on whether they are measurable or not. Categorical data cannot be measured; instead, it can be divided into categories. For example, if Y denotes a person's party affiliation, some examples of Y include...
Drug Products: Biologics, Biosimilars and Interchangeables01:28

Drug Products: Biologics, Biosimilars and Interchangeables

Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...

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Related Experiment Video

Updated: Jul 17, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

Categorical information in pharmaceutical terminologies.

John S Carter1, Steven H Brown, Brent A Bauer

  • 1University of Utah, Salt Lake City, UT, USA.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|January 24, 2007
PubMed
Summary

Drug category labels provide valuable information. The National Drug File - Reference Terminology (NDF RT) covers over 76% of this information, with potential for improvement through new axes and clearer definitions.

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Area of Science:

  • Pharmacology
  • Medical Informatics
  • Drug Information Systems

Background:

  • Drug information sources utilize category labels for organization and navigation.
  • Some category labels encompass multiple drug attributes, such as structure and function.
  • The National Drug File - Reference Terminology (NDF RT) employs a formal reference model with categories like Chemical Structure, Mechanism of Action, Physiological Effect, and Therapeutic Intent.

Purpose of the Study:

  • To analyze the information content of drug category names from multiple sources.
  • To evaluate the semantic coverage of the NDF RT's reference model.
  • To identify areas for improvement in drug information categorization.

Main Methods:

  • Examination of drug category names from three distinct information sources.
  • Assessment of the number of attributes present in category names.
  • Evaluation of NDF RT's coverage against identified attributes.

Main Results:

  • Drug category names, on average, contain more than 1.5 distinct attributes.
  • The NDF RT reference model currently covers over 76% of the information found in drug category labels.
  • Adding a drug formulation axis to NDF RT could enhance coverage to 85%.

Conclusions:

  • Existing drug categorization schemes contain rich information that can guide terminology development.
  • Clarification of concepts like Physiological Effect and Therapeutic Intent is needed.
  • Enhancing NDF RT with additional axes, such as drug formulations, can improve its semantic coverage and fidelity to deployed information sources.