Related Experiment Video
Updated: Jul 17, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Summarizing drug information in Medline citations
Marcelo Fiszman1, Thomas C Rindflesch, Halil Kilicoglu
1Graduate School of Medicine, University of Tennessee, Knoxville, TN, USA.
Abstract:
Adverse drug events and drug-drug interactions are a major concern in patient care. Although databases exist to provide information about drugs, they are not always up-to-date and complete (particularly regarding pharmacogenetics). We propose a methodology based on automatic summarization to identify drug information in Medline citations and present results to the user in a convenient form. We evaluate the method on a selection of citations discussing ten drugs ranging from the proton pump inhibitor lansoprazole to the vasoconstrictor sumatriptan. We suggest that automatic summarization can provide a valuable adjunct to curated drug databases in supporting quality patient care.
Related Concept Videos
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Drug Nomenclature
Drug Discovery: Overview
Drug Absorption: Overview
When drugs are injected intravenously, they directly enter the systemic circulation. Alternatively, orally administered drugs navigate through the gastrointestinal (GI) tract.
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...