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Updated: Jul 17, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Minor increase of endtidal CO2 during sevoflurane-induced malignant hyperthermia
Monalisa Bonciu1, Arnaud de la Chapelle, Henry Delpech
1Département d'Anesthésie-Réanimation Ouest, CHU Nice, Nice, France. monabonciu@yahoo.com
Abstract:
Malignant hyperthermia (MH) in a pediatric patient during sevoflurane anesthesia with only a minor rise of endtidal CO(2) is described. MH was considered because of increased rectal temperature. The outcome was favorable after the initiation of a few simple measures (increased minute ventilation, cessation of sevoflurane). As recommended by the regional MH Reference Center, dantrolene was not used. In vitro contracture tests were performed on muscle biopsies from both parents. A strong contracture in response to halothane confirmed the father's MH susceptibility, thereby according a high probability of an MH episode in his son.
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