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Updated: Jul 17, 2026

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
Published on: June 4, 2020
Elderly people and epilepsy: cognitive function
Ada Piazzini1, Maria Paola Canevini, Katherine Turner
1Epilepsy Center, San Paolo Hospital, Milan, Italy. ada.piazzini@ao-sanpaolo.it
Purpose:
To evaluate cognitive function in a group of elderly patients with focal epilepsy versus healthy controls.
Methods:
A neuropsychological battery assessing major cognitive domains was administered to 40 patients with focal epilepsy aged > or = 60 years, and to 40 controls matched for sex, age, and education.
Results:
Epilepsy patients performed significantly worse in most of the administered tests than controls (p < 0.05). Poor cognitive performances correlated with use of polytherapy.
Conclusions:
Given the high prevalence of epilepsy in the elderly, our results could have important implications for clinical and research purposes.
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