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09:06
Amyloid and the Cross-Beta Architecture
Published on: February 13, 2026
Publishing perishing? Towards tomorrow's information architecture.
Michael R Seringhaus1, Mark B Gerstein
1Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520, USA. michael.seringhaus@yale.edu
BMC Bioinformatics
|January 24, 2007
Summary
Scientific publishing needs modernization to handle vast biological data. Integrating databases with computer-readable articles is key for future bioscience communication.
Area of Science:
- Biosciences
- Bioinformatics
- Computational Biology
Background:
- Traditional scientific articles limit the scope and quantity of biological data that can be published.
- The internet has transformed information access, but scientific publishing formats remain largely unchanged.
- Molecular biology generates vast amounts of factual data, ideal for database storage.
Discussion:
- Scholarly journals and databases play evolving roles in scientific communication.
- Integrating diverse data repositories (genome sequences, protein structures, functional genomics) with traditional publications is crucial.
- Modernizing academic publishing requires exploiting internet capabilities beyond simple online access and hyperlinking.
Key Insights:
- Scientific articles need to become fully computer-readable using intelligent markup and Structured Digital Abstracts.
- A vast proliferation of public and private databases now houses critical biological information.
- The current publishing model cannot fully capture findings from genome-scale research.
Outlook:
- The optimal information architecture for biosciences involves seamless integration of data and publications.
- Tangible steps are needed to improve current scientific information handling.
- Paving the way for an expansive central index is essential for future scientific discovery.
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