Related Experiment Video

Updated: Jul 17, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
07:14

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Published on: May 23, 2025

Lipomatous meningioma

Shigeo Ohba1, Kazunari Yoshida, Takekazu Akiyama

  • 1Department of Neurosurgery, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo 160-8582, Japan. di045009@sc.itc.keio.ac.jp

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|January 24, 2007
PubMed

Insights

This study reports a rare intracranial lipomatous meningioma case. Surgical removal was successful, with detailed histopathological and immunohistochemical analysis of this unique brain tumor.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Pathology

Background:

  • Meningiomas are common primary intracranial tumors.
  • Lipomatous meningiomas are a rare subtype, characterized by adipose tissue infiltration.
  • Understanding their distinct features is crucial for diagnosis and management.

Observation:

  • A 64-year-old woman presented with an intracranial lipomatous meningioma in the parietal convexity.
  • Imaging revealed characteristic features: low density on CT, T1 hyperintensity, and fat-suppressed signal loss on MRI.
  • Gross total tumor removal was achieved.

Findings:

  • Histopathology confirmed a mixed meningioma with transitional and lipomatous components.
  • Immunohistochemistry showed differential expression of EMA, vimentin, and S-100 protein between meningothelial and lipomatous areas.
  • Low Ki-67 indices (1.0% and 1.8%) indicated low proliferative activity in both components.

Implications:

  • This case highlights the importance of recognizing the imaging and pathological characteristics of lipomatous meningiomas.
  • Accurate diagnosis impacts surgical planning and prognosis.
  • Further research into this rare meningioma subtype may refine treatment strategies.

More Related Videos

On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis06:48

On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis

Published on: May 31, 2020

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Related Concept Videos

Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...