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Sydenham's chorea: clinical observations from a Brazilian movement disorder clinic
Vitor Tumas1, Carla Tanuri Caldas, Antonio Carlos Santos
1Ribeirao Preto School of Medicine - USP, Neurology, Psychiatry and Medical Psychology Department, Campus Universitario, Monte Alegre, 14049-900 Ribeirao Preto, Sao Paulo, Brazil. tumasv@rnp.fmrp.usp.br
Abstract:
We retrospectively evaluated the clinical and epidemiological characteristics of 100 patients suffering from Sydenham's chorea (SC). Our analysis revealed a recent, progressive decline in the number of new cases. Onset of SC was frequently reported between 7 and 12 years of age, being more frequent in females. Patients with generalized or severe chorea showed a higher risk of presenting gait abnormalities and behavioral symptoms. Chorea was transitory and remitted within the first 6 months in about 50% of patients but was persistent in 40%. Almost all patients with persistent chorea remitted after a protracted course of the disease.
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