Epilepsy surgery on dysembryoplastic neuroepithelial tumours
S Sayuthi1, J Tharakan, J George
1Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan.
The Medical Journal of Malaysia
|January 24, 2007
Summary
Two rare cases of intractable epilepsy linked to Dysembryoplastic Neuroepithelial Tumours (DNET) highlight varied treatment approaches. Both patients achieved good outcomes after one year, demonstrating effective management strategies for these challenging brain tumors.
Area of Science:
- Neuroscience
- Neurosurgery
- Epileptology
Background:
- Dysembryoplastic Neuroepithelial Tumours (DNET) are rare developmental brain tumors often associated with intractable epilepsy.
- Management of DNET-related epilepsy can be challenging, requiring tailored therapeutic strategies.
Observation:
- This report details two distinct cases of intractable epilepsy stemming from DNET.
- Case 1 involved vagal nerve stimulation and radiosurgery.
- Case 2 utilized neuronavigation-assisted surgical resection.
Findings:
- Both patients experienced favorable outcomes, classified under the Engel scale, after a one-year follow-up period.
- The diverse management approaches, including conservative and surgical interventions, proved effective.
Implications:
- These cases underscore the importance of individualized treatment plans for DNET-associated epilepsy.
- Successful outcomes can be achieved with appropriate neurosurgical and therapeutic interventions.
- Further research into optimal DNET management strategies is warranted.
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